Antibody-mediated disorders

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In antibody-mediated inflammatory disease, B cells (unique white blood cells) produce antibodies against the body's own structures; these are called auto-antibodies. When auto-antibodies bind to these structures, they induce unnecessary inflammation that is directed against healthy tissue. Autoantibodies directed against structures in the brain lead to irritation and swelling of brain tissue. If not treated, long standing inflammation can lead to permanent brain damage and dysfunction.

  • Amyotrophic lateral sclerosis
  • Neuromyelitis optica
  • Schizophrenia
  • Transverse myelitis
  • CNS autoimmunity
  • Guillain-barre syndrome
  • Neurocystercercosis

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