Neurodegeneration and Immune System Interactions

Neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis are increasingly recognized to involve complex interactions between the nervous and immune systems. This session will examine the role of chronic inflammation, immune dysregulation, and protein aggregation in driving neurodegeneration and disease progression. Key topics include the involvement of microglial activation, cytokine signaling, and oxidative stress in neuronal damage. Advances in research have identified potential biomarkers for early detection and monitoring of disease progression, as well as novel therapeutic targets aimed at modulating immune responses. The session will also discuss current challenges in treatment, ongoing clinical trials, and future directions in developing disease-modifying therapies that can slow or halt neurodegenerative processes.

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